Perspectives

Clinical Thinking,
Shared Openly

How we evaluate evidence, make decisions, and navigate the boundary between what medicine knows and what it doesn't — yet.

Evidence Review Kendrick Lopez, MD February 26, 2026

What Your Annual Physical Actually Misses

A Cochrane review of 250,000 participants found annual physicals don't reduce mortality. Here's what the standard visit misses, what the evidence says you should be measuring instead, and why the format is the problem.

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Evidence Review Kendrick Lopez, MD February 25, 2026

Let's Start with Peptides...

A member texted at 9pm: "What about peptides?" Here's what we told her — and what the evidence actually says about BPC-157, GHK-Cu, and the difference between promising and proven.

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